Pharvaris Careers

Pharvaris is a late-stage biopharmaceutical company developing novel, oral bradykinin B2 receptor antagonists to potentially address all types of bradykinin-mediated angioedema. By targeting this clinically proven therapeutic target with novel, oral small molecules, the Pharvaris team is advancing new alternatives to injected therapies for the prevention and treatment of hereditary angioedema (HAE) attacks, and other bradykinin B2-receptor-mediated indications. HAE is a rare and potentially life-threatening genetic disease and people living with HAE can suffer sudden and prolonged attacks of swelling in multiple areas of the body including the airway, which can be life-threatening.

We are expanding our global Medical Affairs team and are looking for a Scientific Publications Lead, to join our team and report to our Senior Director of Medical Affairs.  

If you are looking for a place where your work can have meaning, and you can make a difference – Pharvaris is the place for you.

Location

We have offices in Switzerland (Zug), the Netherlands (Leiden) and the USA (greater Boston area) and, at Pharvaris, we promote and enable a flexible hybrid work environment where our employees choose from where (and to some extent when) they prefer to work. Whilst this is a remote/hybrid role, you need to be based in either the U.S. (East coast), the Netherlands or Switzerland. For this role we are focusing on talent over location.

Scope

Responsibilities for this role include:

• Executing the global scientific publications strategy, ensuring alignment with the medical and company strategy
• Developing, managing and delivering the annual publications plan, including manuscripts, abstracts, congress presentations and posters
• Managing the end-to-end publications process (from development to journal submission and congress presentation)
• Managing relationships with KOLs, authors and external vendors to facilitate smooth collaboration and timely publication
• Overseeing the creation of high-quality scientific content, ensuring all publications adhere to Good Publication Practices (GPP), industry standards
• Translating complex scientific data into clear, compelling and compliant medical content for diverse audiences, including medical education materials
• Partnering cross-functionally with Medical Affairs, Patients Advocacy, Early Development, Clinical Development, and Evidence, Value and Outcomes Research to develop and align publication strategies aligned with company imperatives
• Supporting advisory boards, speaker programs, medical education activities and (scientific) symposia with key publications and medical content
• Maintaining awareness of the latest trends and advancements in the pharmaceutical industry to drive innovation and improve publication practices
• Working closely with the legal and compliance team to ensure all ethical information and publications activities meet legal and ethical standards
• Ensuring proper archiving and documentation of publication materials in compliance with company policies and regulatory requirements

Requirements/Key Attributes

• Advanced scientific degree (PhD, PharmD, MD or MSc), preferably in life sciences or another health-related field
• Preferably 5 years+ global experience in publication management or medical communications (in a pharmaceutical/biotech environment), ideally in the field of rare disease or, more specifically, hereditary angioedema (HAE)
• Preference for candidates who have worked for emerging biopharmaceutical companies in the past, with evolving operating procedures and employee remits
• Prior leadership or cross functional team experience (managing vendors, overseeing projects, leading publications planning)
• Experience working in a highly regulated environment, preferably familiar with ICMJE, GPP, and other international standards for ensuring the quality and transparency of publications
• Proficiency using medical/scientific publication databases/resources and project software
• Proficiency in Microsoft Office (Word, PowerPoint, Excel, Outlook)

We are looking for someone that has:

• Good attention to detail with critical and analytical skills
• Excellent communications skills (verbal and written)
• Excellent project management skills
• Problem solving skills
• Results-oriented
• Strong team player with an international mindset
• Natural ability to influence and lead projects

Interested?

Please send your resume to [email protected]. We look forward to speaking to you.

Pharvaris is a late-stage biopharmaceutical company developing novel, oral bradykinin B2 receptor antagonists to potentially address all types of bradykinin-mediated angioedema. By targeting this clinically proven therapeutic target with novel, oral small molecules, the Pharvaris team is advancing new alternatives to injected therapies for the prevention and treatment of hereditary angioedema (HAE) attacks, and other bradykinin B2-receptor-mediated indications. HAE is a rare and potentially life-threatening genetic disease and people living with HAE can suffer sudden and prolonged attacks of swelling in multiple areas of the body including the airway, which can be life-threatening.

If you are looking for a place where your work can have meaning, and you can make a difference – Pharvaris is the place for you.

To support our lead programs aimed at bringing new, novel oral options to people living with HAE, we have an opportunity for a highly driven (Senior) Manager, Clinical Supply to join our Clinical Supplies Team and help implement our strategy and vision.

If you are a hands-on and pragmatic individual – inspired by building effective solutions for patients and passionate about balancing pragmatism with high quality – this could be the role for you.

Location

At Pharvaris we promote and enable a flexible hybrid work environment, where our employees choose from where (and to some extent when) they prefer to work. Given the nature of this role and the teams you will be working with, this position will be based in either The Netherlands (preferred), or Switzerland.

Scope

This role will be responsible for End-to-End Clinical Supply Chain Management, in an unblinded fashion, starting from forecasting up until destruction of supplies for Pharvaris-sponsored Phase 1-3 clinical trials, as well as other trials with Pharvaris’ investigational product (e.g. Investigator Initiated Trials, Collaborative Research Trials). This role will plan and implement the overall unblinded supply chain strategy and will represent Clinical Supplies in internal and external supplier team meetings. Other responsibilities include:

• Ensure consistent, reliable, and compliant supply of clinical products (including IMP, AxMP and ancillary supplies) in accordance with the forecast and inventory requirements, the planning assumptions, and supply budget
• Act as an intermediate between Manufacturing, Quality, Clinical Supply, Distribution and Clinical Operations partners
• Develop and manage relationships with key external business partners, to ensure product supply and clinical needs are met
• Collaborate with other stakeholders to conduct supply chain risk management process
• Manage distribution strategies, both at the depot level and site level
• As the unblinded study team member, ensure proper study information flow to maintain the study blind
• Use IRT for inventory management. Work with IRT Lead on IRT set up (UATs and IRT spec integration)
• Work with appropriate functions to help generate randomization lists
• Monitor, track and proactively manage IMP expiry
• Work with Quality, Regulatory and Clinical partners on study close outs
• Work with Quality, Clinical Operations and Distribution partners to manage, track and close out product complaints including in-transit and at-site temperature excursions
• Establish excellent working relationships with CMC, Quality, Clinical Operations, and Finance functions and forge integrated ways of working to efficiently manage and report on the flow of product and information

Requirements/Key Attributes

• BSc (MSc preferred) in Pharmaceutical or Life Science, Business, Supply Chain Management, or related fields
• 6+ years of pharmaceutical industry experience
• 3+ years of global clinical supply chain experience
• Operational level supplier relationship management experience
• Broad knowledge base of supply chain operations
• Working knowledge of regulated manufacturing, GMP, and quality systems
• Demonstrated complex problem-solving ability and sound judgement ability to deal with ambiguity and work towards bringing clarity
• Demonstrated business acumen and influencing skills
• Excellent written, oral communication, and presentation skills along with the ability to communicate effectively
• Good team player with result-oriented attitude and can-do mentality

Interested?

Please send your resume to [email protected]. We look forward to speaking to you.