Pharvaris’ dynamic environment offers our employees the opportunity to discover and develop innovative therapies. We are looking for dedicated employees to join our international team. Please send your full resume and application letter to our HR department at .

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Financial Accountant

Pharvaris, a public and clinical stage company developing bradykinin B2 receptor antagonists for bradykinin-mediated diseases, has an opportunity for a highly motivated Financial Accountant. The company is based internationally and growing quickly. As a result of this growth, we are expanding our finance team and looking for a financial accountant in Leiden, the Netherlands.



This role is based in Leiden, NL. Pharvaris supports its staff to be home based and work virtually



The financial accountant is part of the finance department and will report to the Executive Director Finance & Administration, based in Leiden NL. The financial accountant works closely with two other Financial Accountants, Financial Controller, SG&A/ R&D FP&A and Payroll Accountant. The duties of this role include but are not limited to responsibility for financial accounting functions, with the main focus on purchase to pay (AP). Additional responsibilities are assisting in the Record-to-Record (GL) and related activities.


Roles and Responsibilities:

  • Creation and maintenance of the vendor master files
  • Recording of invoices as specified by the policies of the company
  • Reviewing all invoices for appropriate characteristics, documentation and required authorisation prior to payment
  • Preparation of weekly payments
  • Recording routine transactions
  • Cash flow requirement forecasts
  • Manage general ledger accounting activities by ensuring accuracy and timeliness of cut off, journal entry postings, reconciliations, and month-end close activities
  • Assisting and collaborate with the payroll accountant to ensure timely and accurate processing of payroll and submission of social security and payroll tax returns
  • Processing and reconciliation payroll
  • Performing internal control validations to verify the integrity of all systems, processes, and data
  • Preparing and filing VAT returns, prepares adjusted VAT returns, when necessary, per quarter
  • Assisting in the contract management process, by documentation and filing of contracts.


  • Bachelor’s degree, or MBO level 4 diploma in accounting, bookkeeping or similar
  • 2+ year of experience as financial accountant. Experience in an international, life science and public reporting environment is a pre.
  • High proficiency in English, written and spoken
  • Working knowledge of accounting, including IFRS, Dutch, Swiss and US GAAP.
  • Experience with ERP systems and proficiency with Microsoft Excel.
  • Excellent analytical skills with strong attention to detail in planning, organization, and execution of tasks.
  • Good understanding of processes and procedures.
  • Accurate and an eye for detail.
  • Feels comfortable in a fast-paced, international, and dynamic environment
  • Result oriented attitude and can-do mentality.
  • Clear and intelligent communicator
  • Open-minded and creative problem solver, who is punctual, takes ownership, and has ability to deal with competing priorities and challenges.


How to apply?

This position is within a highly collaborative and dynamic department that strives to achieve high quality financial data. This role is based in the Netherlands (Leiden) and reports to the ED Finance & Administration. We offer our staff a great and flexible working environment, dedicated and driven co-workers, short lines of communications and an attractive compensation package.


If you are interested to be part of a great and dedicated team at Pharvaris, please send your full resume and application letter to our HR department, .

Senior Manager / Associate Director, Biostatistics

Pharvaris – a clinical-stage company focused on bringing an oral bradykinin B2 receptor antagonist to patients – is seeking a highly motivated Senior Manager / Associate Director of Biostatistics to join the Biometrics organization with dedication to fast-paced ph2-3 programs and ensure impeccable design, execution, and readout of key clinical trials.

This position is within a highly collaborative and international department that strives to achieve high quality and excellent results. This role may be based in the Boston area (MA USA), Zug (Switzerland) or in Leiden, the heart of biotech in The Netherlands and reports to the Head of Biometrics, who is based in the USA. We offer talented staff a great working environment, dedicated and driven co-workers, short lines of communications and an attractive compensation package.


  • Serve as biostatistics lead for multiple key clinical studies and ensure all business deliverables pertaining to statistics compliant with GCP standards, ensure high quality and efficiency in analysis outputs (analysis datasets, tables, figures, and listings) and documentations.
  • Manage and provide direct oversight for the counterpart at CROs in support of all clinical trials. Provide technical leadership and close governance on statistical activities conducted both inhouse and at the vendor’s side.
  • Provide guidance to statistical programming team on SDTM/ADaM and TLFs specs development, data variable definitions and sample code for statistical procedures. Perform quality control checks of analysis datasets creation and statistical analyses.
  • Provide input to database requirements and work closely with CDM to ensure data quality standards following regulatory requirements.
  • Support CDM, Clinical Operations and Medical Monitors to design and perform in-depth data checks and cleaning during trial conduct through final database lock.
  • Contribute to building quality-controlled analyses supporting regulatory queries, publications, regulatory safety reports, and other ad-hoc business deliverables.
  • Effectively explain statistical methodology and analysis results to cross-functional teams and support regulatory interactions. Provide exploratory analyses to facilitate and reinforce the collaboration with internal and external stakeholders, ensure effective partnerships across development teams.


  • PhD in statistics (or equivalent) with at least 4 years of experience, or MS in statistics (or equivalent) with a minimum of 8 years of experience working in clinical trials or biomedical research.
  • Demonstrated excellence in statistical capabilities across multiple areas of pharmaceutical biostatistics, together with good understanding of GCP standards and the drug development process. Preferred with experience working on pivotal clinical trials.
  • Broad knowledge of advanced statistical concepts with excellent hands-on skills. Strong technical expertise and programming skills in SAS and standard statistical computing systems.
  • Demonstrated strong organization skills with ability to manage multiple projects/studies.
  • Strong teamwork skills with result-oriented attitude and can-do mentality.
  • Excellent technical writing and verbal communication skills.
Clinical Quality Assurance Director

Pharvaris, a public and clinical stage company developing bradykinin B2 receptor antagonists for bradykinin-mediated diseases, has an opportunity for a highly motivated Clinical Quality Assurance Director to join and help drive bringing solutions to patients


This role is based in Europe, this may be Leiden, NL or Zug, CH or in the Boston region, US.  Pharvaris supports its staff to be home based and work virtually.


The CQA Director will lead quality activities and be responsible for establishing and leading the Clinical QA function. This position will oversee the global GCP and Clinical Quality function and represent the company as the key CQA liaison with external vendors and CROs. The incumbent will be responsible for the company’s clinical quality systems and compliance strategies involving clinical trials and global marketing preparations. The Director will also be expected to work with key business partners to assure compliance with GCPs and GLPs in an effective and efficient manner. The incumbent is responsible for evaluating and ensuring compliance of clinical studies with global regulatory agencies.  

The Director will provide oversight of Clinical QA systems and ensure compliance with clinical research activities.  The candidate must have the ability to develop and implement GCP-related quality systems and training of staff and be able to oversee audit plans and activities so as to conduct effective audits of investigator sites, documents, Trial Master Files, vendors, and internal and external processes.

The CQA Director will be responsible for planning, coordinating, controlling, and continuously improving the internal GCP-QA processes and systems.  They will assure quality awareness in conducting clinical studies and convey confidence in clinical knowledge providing a strong understanding of clinical processes.  The Director will be expected to routinely interact with external partners to promote collaboration and ensure all systems, processes, and their outcomes are compliant with applicable international standards, regulations and guidelines.  The candidate should have the ability to actively leverage audit outcomes and trends to inform improvements in conducting clinical trials and reporting while championing the highest standards of compliance.


Key Responsibilities:

  • Identify and communicate GCP quality and compliance risks and implement appropriate plans for resolving issues and addressing risks
  • Develop and provide training on GCP topics
  • Identify Quality processes/system that require implementation or improvements
  • Work with the Clinical Operations team to develop and maintain audit programs for clinical sites with appropriate risk assessment and mitigation
  • Plan, conduct and report on GCP audits of clinical investigators, vendors, systems as well as key reports and documents to facilitate regulatory inspections
  • Prepare and revise GCP SOPs and Work Instructions as well as creation and maintenance of audit tools
  • Represent GCP QA on project teams to facilitate audit planning both internally and externally
  • Work with cross-functional teams to provide GCP advice and provide guidance on risk- based QA audit options
  • Review clinical study documents and check for consistency and appropriate standards and practices



  • Bachelor’s degree life science

Work experience:

  • 5+ years of direct GCP QA experience with a least 10 years in pharmaceutical/biotech industry, trained and certified GCP auditor.
  • Language fluency in English
  • Personal skills and other competencies, as needed: goal-oriented, completer/finisher, recognition of inter-cultural differences
  • Experience to work in a matrix, ability to influence without authority
  • Demonstrated record of team skills: comfortable in an interdisciplinary and international environment and able to communicate effectively and to collaborate in a team
  • Comfortable in a small company environment that is fast paced, challenging and where all leaders must take on a hands-on approach to get results
  • Ability to multi-task and manage workload independently
Senior Payroll & HR Operations Lead

Pharvaris is a public and clinical stage company developing bradykinin B2 receptor antagonists for bradykinin-mediated diseases. To support our lead program aimed at bringing new, oral options to patients suffering from hereditary angioedema (HAE), we are looking for a highly motivated Senior Payroll & HR Operations Lead to join the HR team and help drive bringing solutions to patients.

If you are an individual who has a natural intellectual curiosity, strong analytical skills, the ability to flex easily between operational and tactical work, and the desire to drive process improvement., this could be the role for you!



This role is based in the Netherlands, preferably in Leiden, but we are open to remote Netherlands based employees as well.  At Pharvaris, we promote and enable a flexible hybrid work-environment, where our employees choose from where (and to some extent when) they prefer to work.   



The Senior Payroll and HR Operations Lead is an individual contributor, key member of the HR team and works across 3 geographies (US, NL, and CH) in support of Pharvaris’ global operations.  In this role, you are the face of Operational HR to employees, external partners, and senior management at Pharvaris.

You will continue to build a streamlined onboarding experience for Pharvaris new joiners, provide a first-class payroll & benefits experience to the existing teams, and improve the overall employee experience through new HR Operations initiatives and ideas.


In this role, you will work cross-functionally with internal stakeholders (Accounting, Financial Reporting, Office Management) and external teams (payroll and benefits partners, equity platform partner).


What you will be responsible for:

  1. Payroll and Benefits Management
  • Ensure an accurate and timely payroll, including but not limited to base pay, equity compensation, payroll taxes, statutory and supplemental benefits, etc.
  • Manage relationships with (3) external Payroll providers and benefits providers for the Netherlands, Switzerland, and US.
  • Own month-end close, quarter-end and year-end processes for all Pharvaris entities including reviewing/approving journal entries, account reconciliations and accruals
  • Ensure all payroll regulatory filings are completed timely and accurately
  • Partner closely with Finance and HR Leadership to drive global payroll strategy and streamline processes to ensure consistency, accuracy, and best-in-class services
  • As we continue to grow, lead payroll development and implementation process for new countries or entities
  1. HR Operations
  • Lead the design, development, and communication of Pharvaris´ employee handbook(s) – capturing global and local people guidance and principles
  • Partner with Office Management to design and implement top notch employee onboarding and orientation process
  • Ensure Pharvaris´ recordkeeping and data processing procedures comply with GDPR requirements
  • Manage the visa and immigration process where relevant
  • Work with employees and managers to manage leave of absence in accordance with local legislation
  • Handle employee queries regarding HR procedure, policy, benefits programs
  • As we grow, represent HR Operations on the creation of new legal entities
  • Participate in and lead ad hoc projects when required


  1. Continuous improvement
  • Champion a strong continuous improvement culture to ensure deployment of scalable, simplified, and standardized processes
  • Find opportunities for continuous improvement of administrative processes, procedures and approaches for consistency, accuracy, and compliance
  • Proactively prepare relevant management reports, metrics and statistics as needed
  • Stay current on regulations, benefits changes, and labor laws impacting the payroll process, and stay compliant for all payroll tax jurisdictions

What you absolutely need to bring to the table to be a credible candidate for this role:

  • At minimum a bachelor’s degree in Finance/Tax/Accounting/HR (or equivalent professional experience)
  • Minimum of 5 to 7 years of experience in managing the end-to-end global payroll process and a high level of understanding of general business operations and internal control concepts
  • Hands on knowledge of payroll across Europe – knowledge of US payroll is a plus
  • Knowledge & understanding of international equity and mobility programs
  • Advanced skills with Excel and other Microsoft Office products
  • Fluency in English (working language)

Some other elements that will make you set up for success in this role:

  • Experience with complex cross-functional payroll projects, integrations, and implementations
  • Understanding of timekeeping regulations and processes
  • Having a ´can do, roll up my sleeves´ mentality, with an excellent ability to prioritize effectively and ruthlessly to meet multiple tight deadlines
  • Taking pride in building a positive employee experience
  • Being a confident communicator and team player who can build strong working relationships with external advisors, internal teams, and employees at all levels
  • Having a strong feel for numbers and data – strong analytical skills, taking high pride in being accurate and detail-oriented.
  • Proactive and excellent ability to initiate and self-start complex projects
  • Feeling comfortable handling ambiguity and change
  • Being an avid and quick learner, not afraid to ask questions


We offer talented staff a great working environment, dedicated and driven co-workers, short lines of communications and an attractive compensation package. If you are interested to be part of a small, and fun HR team at Pharvaris, please reach out and send your full resume and application letter to us, .  

Looking forward to meeting you soon…!

Director, Corporate Development

Pharvaris, a public and clinical stage company developing bradykinin B2 receptor antagonists for bradykinin-mediated diseases, has an opportunity for a highly motivated Director, Corporate Development to join and help drive our corporate development to bring more choices to patients.


Reporting to the Chief Business Officer, the Director will work closely with internal and external senior leaders to successfully support overall corporate development goals including preparation, sourcing, negotiation, and execution of transactions supporting R&D and commercial.


Flexible, ideally in United States or in Europe (Switzerland, the Netherlands). Pharvaris supports its staff to be home based and work virtually.


  • Develop and maintain an expert understanding of the scientific and asset landscape and competitive intelligence to ensure visibility to emerging opportunities and changes in the environment
  • Identify & source compelling external opportunities; lead the review of R&D stage opportunities to assess their viability and drive to a prioritization decision.
  • Design partnership roadmaps, conduct initial outreach to prospective companies, and advocate to senior leadership for specific deals in support of portfolio and business team priorities
  • Follows up on all partnership activity including the tracking, documentation and status reporting of all collaborations along the business development pipeline
  • Serve as the liaison with the third party for all interactions that progress beyond initial review
  • Build and maintain valuation, statistical and financial models that incorporate industry standard information sources, valuation methods, and statistically relevant data
  • Manage the preparation of term sheets, contracts, business cases, valuation models and other materials in collaboration with Legal, IP and other functions as required
  • Manage necessary cross-functional due diligences and will collaborate with cross-functional teams to deliver and execute eventual deals and manage any transition to the alliance management function
  • Support deals and contract in partnership with legal, finance and other areas
  • Establish and strengthen relationships with potential external partners


  • Minimal Bachelor’s degree in science or related field; advanced scientific degree relevant to pharmaceutical R&D (PhD, PharmD or MD) strongly preferred
  • Strong track record of success in positions of increasing responsibility; minimum of five years of broad-based business experience; relevant experience includes, but is not limited to corporate or business development/planning, corporate strategy, consulting, or investment banking
  • Experience in biotech or pharma deal making, including opportunity sourcing, due diligence, asset valuation, deal structuring, and negotiations
  • Robust understanding of the full drug development process, life-cycle management, and commercialization of therapeutics
  • Proficient biopharma commercial/market awareness with good understanding of key drivers that underpin commercial assessments and valuations
  • Strong skills in representing business cases and driving timely and smart decisions across complex internal and external organizations
  • Excellent planning and organization skills and an ability to prioritize effectively to deliver results within aggressive timelines with the ability to work independently and as part of a team
  • A team player with demonstrated ability to align people and resources towards organizational success
  • Ability to thrive in a dynamic environment with high level of agility; a wide degree of creativity and strategic thinking is expected
  • Excellent executive communications skills – both oral and written
  • Comfortable in a small company environment that is fast paced, challenging and where all leaders must take on a hands-on approach to get results.
  • Ability to multi-task and manage workload independently