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Pharvaris’ dynamic environment offers our employees the opportunity to discover and develop innovative therapies. We are looking for dedicated employees to join our international team. Please send your full resume and application letter to our HR department at .

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Director, Corporate Development

Pharvaris, a public and clinical stage company developing bradykinin B2 receptor antagonists for bradykinin-mediated diseases, has an opportunity for a highly motivated Director, Corporate Development to join and help drive our corporate development to bring more choices to patients.

Description

Reporting to the Chief Business Officer, the Director will work closely with internal and external senior leaders to successfully support overall corporate development goals including preparation, sourcing, negotiation, and execution of transactions supporting R&D and commercial.

Location

Flexible, ideally in United States or in Europe (Switzerland, the Netherlands). Pharvaris supports its staff to be home based and work virtually.

Responsibilities

  • Develop and maintain an expert understanding of the scientific and asset landscape and competitive intelligence to ensure visibility to emerging opportunities and changes in the environment
  • Identify & source compelling external opportunities; lead the review of R&D stage opportunities to assess their viability and drive to a prioritization decision.
  • Design partnership roadmaps, conduct initial outreach to prospective companies, and advocate to senior leadership for specific deals in support of portfolio and business team priorities
  • Follows up on all partnership activity including the tracking, documentation and status reporting of all collaborations along the business development pipeline
  • Serve as the liaison with the third party for all interactions that progress beyond initial review
  • Build and maintain valuation, statistical and financial models that incorporate industry standard information sources, valuation methods, and statistically relevant data
  • Manage the preparation of term sheets, contracts, business cases, valuation models and other materials in collaboration with Legal, IP and other functions as required
  • Manage necessary cross-functional due diligences and will collaborate with cross-functional teams to deliver and execute eventual deals and manage any transition to the alliance management function
  • Support deals and contract in partnership with legal, finance and other areas
  • Establish and strengthen relationships with potential external partners

Requirements

  • Minimal Bachelor’s degree in science or related field; advanced scientific degree relevant to pharmaceutical R&D (PhD, PharmD or MD) strongly preferred
  • Strong track record of success in positions of increasing responsibility; minimum of five years of broad-based business experience; relevant experience includes, but is not limited to corporate or business development/planning, corporate strategy, consulting, or investment banking
  • Experience in biotech or pharma deal making, including opportunity sourcing, due diligence, asset valuation, deal structuring, and negotiations
  • Robust understanding of the full drug development process, life-cycle management, and commercialization of therapeutics
  • Proficient biopharma commercial/market awareness with good understanding of key drivers that underpin commercial assessments and valuations
  • Strong skills in representing business cases and driving timely and smart decisions across complex internal and external organizations
  • Excellent planning and organization skills and an ability to prioritize effectively to deliver results within aggressive timelines with the ability to work independently and as part of a team
  • A team player with demonstrated ability to align people and resources towards organizational success
  • Ability to thrive in a dynamic environment with high level of agility; a wide degree of creativity and strategic thinking is expected
  • Excellent executive communications skills – both oral and written
  • Comfortable in a small company environment that is fast paced, challenging and where all leaders must take on a hands-on approach to get results.
  • Ability to multi-task and manage workload independently
Program Manager Clinical - Associate Director

Pharvaris, a clinical stage scale-up company developing bradykinin B2 receptor antagonists for bradykinin-mediated diseases, is seeking a highly motivated Program Manager Clinical to join and help drive our drug development efforts. 

The Program Manager Clinical (Associate Director level) is a member of the (global) program management team and will pro-actively support clinical development leadership and the clinical and regulatory teams to ensure integration of the clinical and regulatory strategy in the integrated program planning. You will be part of a highly internationalized enthusiastic team with high professional and scientific standards, eager to bring our solutions to the HAE patient community, using a hands-on and pragmatic approach.

Location

This role may be based in the United States (Boston area) or in Europe, either in Leiden, the Netherlands or Zug, Switzerland. Pharvaris supports its staff to be home based and work virtually.

Key Characteristics (Objectives and Responsibilities)

  • Provide project management support to clinical and regulatory teams, and/or (operational) sub-teams
  • Integrate clinical and regulatory plans in the integrated project planning (timelines, milestones, interdependencies) and identification/management of critical path
  • Consolidate and communicate comprehensive information regarding clinical and regulatory strategy and plans to R&D and other functions, by developing, improving, and maintaining operational cadences (e.g., team meetings, internal communications)
  • Support defining, implementing, and executing an optimal workflow for all clinical and regulatory budget processes (PO’s, contractors, invoicing, etc.). Help driving clinical and regulatory budget development and budget tracking
  • Continuous improvement of project management (tools) in the organization

Main activities

  • Organize meetings and agenda setting, drive minutes, follow up on actions and decisions.
  • Drive team alignment on the clinical development programs, regulatory strategy, clinical supply chain and other key topics/events related to clinical product development, in the form of an integrated Clinical Development Plan or equivalent
  • Gather, coordinate, consolidate information from different forums and levels (e.g., clinical study teams, project leaders, function heads) and present in an appropriate format, such as but not limited to:
    • Program Gantt / key events map / integrated project planning
    • Risk management plan
    • Interdependencies between projects and/or functional areas for timelines, resources, quality and/or budget
    • Executive summary/ status reporting
  • Keep all stakeholders (e.g., Program Management and clinical and regulatory teams and others as applicable informed of progress and changes
  • Support leadership in budget development and support Finance in budget planning and tracking

 

Job Holder Requirements/Key competencies:

  • Education: Advanced degree in a life science discipline, or equivalent by experience
  • Minimal work experience: At least 10 years of relevant experience in pharma/biotech product development, of which at least 5 years in clinical development and/or project management
  • Personal skills and other competencies, as needed:
    • Ability to translate clinical and regulatory project needs into activities that are appropriate for the phase of the program/project
    • Ability to see and understand the big picture while knowing the importance of details, manage workload independently and meet tight deadlines
    • Open personality with proven team spirit and excellent managerial, communication and collaboration skills in a cross-functional, international environment
    • Excellent interpersonal skills with the ability to pro-actively adapt in a small company environment that is fast paced, challenging and requires a hands-on approach
    • Excellent knowledge of project management tools, including principles of strategic planning, conflict resolution, negotiation skills, costs monitoring and organization responsibility charts
    • Knowledge and understanding of ICH-GCP guidelines and other applicable regulatory guidelines
    • Excellent verbal and written communication and presentation skills (English is working language)

 

Deputy General Counsel & Compliance Officer, Vice President

Pharvaris is dedicated to pioneering science for patient choice, specifically bradykinin B2 receptor antagonists for hereditary angioedema (HAE) and other bradykinin-mediated diseases. It is a clinical-stage company with a portfolio of pre-commercial assets aimed at bringing new, more convenient options to HAE patients who suffer sudden and prolonged attacks of swelling in multiple areas of the body including the airway and can be life-threatening.

Headquartered in Zug, Switzerland, with hubs in the Greater Boston and Amsterdam areas, we have a culture built on the core values of caring, trust, diversity and freedom and is driven by individuals committed to developing breakthrough therapies that have real impact on people’s lives.

If you are looking for a place where your work can have meaning and you can make a difference – Pharvaris is the place for you.

We are currently seeking a highly motivated Deputy General Counsel & Compliance Officer, Vice President to join our growing global Legal and Compliance (LECO) Team.

Location

At Pharvaris we promote and enable a flexible hybrid work environment, where our employees choose from where (and to some extent when) they prefer to work. Given the nature of this role, we would like this position to be based in the US, preferably on the East Coast. 

Role 

In this newly created role, you will have the opportunity to help build the global Legal & Compliance Team from the ground up as Pharvaris scales the organization for Phase 3 development and ultimately commercialization. Reporting directly to the Chief Legal Officer (CLO), you will lead the implementation of a business-enabling compliance program aligned with our core values and you will partner with the CLO to navigate the full-range of legal matters affecting the company including corporate and commercial transactions, litigation, employment, among other areas.

You will partner closely with our teams in commercial, medical affairs, regulatory, quality, patient advocacy, human resources and finance, among others. You will work cross-functionally and internationally with operating units throughout our organization to lead and support legal and compliance initiatives, and to raise the level of awareness of compliance and legal risk management within our organization.

Key Characteristics of the Role (Objectives and Responsibilities)

  • Closely partner with the CLO to drive the LECO strategy and build and scale a “fit for purpose” function as the Pharvaris organization grows and the company advances the development of its pipeline.
  • Provide broad-based legal advice and support to the business in corporate and commercial transactions, litigation, employment, among other areas.
  • Establish and refine Pharvaris’ compliance program in accordance with developing industry guidance and trends and ensure the compliance program is effectively integrated into the culture and business operations.
  • Continue to reinforce a culture of integrity and raise awareness of compliance as a collective responsibility of all company personnel through effective engagement, training, auditing, and monitoring.
  • Provide strategic compliance advice to the business to ensure compliance with applicable U.S. laws and company policies, including federal and state antikickback and false claims laws, the federal Food Drug and Cosmetic Act (FDCA) laws, the PhRMA Code, state laws, federal and state transparency laws, and antitrust laws.
  • Manage budgets and external counsel activities.

Job Holder Requirements/Key competencies:

  • Law degree from an ABA-accredited law school or equivalent degree earned in a non-US country.
  • Licensed to practice law in one or more of the fifty (50) states within the US.
  • At least ten (10) years’ experience in senior leadership roles within legal and compliance, preferably in life sciences.
  • Prior in-house experience preferred.
  • Fluency in English (working language).

    Personal skills:

    • High ethical standards and integrity and courage to speak up and voice dissent or concern.
    • Perspective and judgment to assess what is really important and prioritize in a fast-paced environment.
    • Excellent interpersonal skills with the ability to pro-actively adapt in a small company environment that is fast paced, challenging and requires a hands-on approach.
    • Composure and credibility when addressing challenge and conflict.
    • Emotional intelligence, flexibility and solution orientation.
    • Strong understanding of the functional operations within commercial, research and development, finance, quality and human resources in the life sciences space.
    • Ability to communicate complex concepts in ways that are understood by cross-functional teams.
    • Ability to cultivate strong stakeholder relationships and successfully influence senior leadership and peers.
    FP&A Lead, Associate Director

    Pharvaris, a public and clinical stage company developing bradykinin B2 receptor antagonists for bradykinin-mediated diseases, has an opportunity for a highly motivated, FP&A Lead to join and drive our financial planning and analysis. The FP&A Lead acts as a finance business partner to the different G&A and Commercial Leaders, and implements, develops and provides financial analysis on KPIs, and utilizes data gathered to render business recommendations and decisions. You will perform month-end close G&A and Commercial activities, actively manage risks and opportunities, and lead scenario planning and resource management. You will also lead process improvement initiatives and influence key initiatives within G&A and Commercial functions.

    Location

    Flexible, ideally in Europe (The Netherlands, Switzerland). Pharvaris supports its staff to be home based and work virtually

    Core activities/ Areas of result

    • Drives FP&A business plans for allocated departments and enhances ‘best in class’ performance – contributes to the Annual Operating Plan and to the Long-Range Planning Process, coordinating with business leaders to develop yearly budgets and 3-year business plans, including booking, revenue, recurring revenue, expenses and all relevant KPIs.

    • Develops and continuously improves tools, processes and systems to support streamlined, transparent, efficient and robust budget and planning preparation as well as budget vs. actuals measurement.

    • Ensures financial management and reporting according to corporate policies and procedures, ratios, and reporting formats to have an ongoing insight on the financial effects of the department operations. Allocates costs according to budget.

    • Takes ownership of the consolidation and reporting of all financial information –budgets, planning, forecasts-, according to corporate policies and procedures to provide actual and accurate information of the financial position.

    • Joins in the efforts to improve various reporting cycles, leading the monthly / quarterly forecasting process for allocated departments.

    • Prepares Budget/ Forecast variances to Actuals for internal and external reporting.

    • Prepares presentations for the Executive Committee and Board of Directors.

    • Is responsible for communications with all stakeholders to provide business solutions, deliverables and discuss results to ensure an excellent availability of financial information on aggravated levels.

    • Coordinates and monitors data collection and report flows, reviews and policies and procedures to facilitate the information flow to management levels of high-quality analysis and information. Identifies trends and communicates conclusions and recommendations.

    • Oversees all financial commitments of the G&A and Commercial organization, supports the monthly accrual process and quarterly and year-end financial audits.

    • Contributes to the continued development of the FP&A strategy, policies and procedures, advises the Head of Finance on deliverables, business solutions and policies and procedures.

    • Supports M&A and integration efforts, including due diligence and integrating acquired companies into the organization forecasting and reporting framework, process and timelines.

    • Leads, executes or supports various ad hoc projects/ initiatives in Finance and business network

     

    Requirements

    • Minimal Bachelor’s degree in Accounting, Finance, or similar

    • 6 -10 years’ experience in a multinational highly competitive and quality focused environment

    • Excellent knowledge of start-up operations and structures

    • FP&A experience involving coordination of financial planning processes and month end close

    • Advanced proficiency in Microsoft Excel and PowerPoint with familiarity of Microsoft Dynamics and Power BI

    • Strong problem solving, analytical and communication skills

    • Excellent planning and organization skills and an ability to prioritize effectively to deliver results within tight timelines

    • Team player with demonstrated ability to align people and resources towards organizational success

    • Ability to thrive in a dynamic environment with high level of agility; a wide degree of creativity and strategic thinking is expected

    • Excellent executive communications skills – both oral and written. English is company language.

    • Comfortable in a small company environment that is fast paced, challenging and where all leaders must take on a hands-on approach to get results

    • Ability to multi-task and manage workload independently